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HRID533506

反应详情

EQUATION

反应方程式

HRID 533506 的结构方程式

REACTANTS

反应物

3
结构：CC1(C)OB(B2OC(C)(C)C(C)(C)O2)OC1(C)C
HCID2733548

Bis(pinacolato)diboron

C12H24B2O4

结构：CCOC(=O)[C@@](C)(CCc1ccc(Br)cc1)S(C)(=O)=O
HCID66578009

未命名化合物

结构：CCOC(=O)C(C)(CCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)S(C)(=O)=O
HCID66578081

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)[C@@](C)(CCc1ccc(B2OC(C)(C)C(C)(C)O2)cc1)S(C)(=O)=O
HCID66577950

未命名化合物

收率 93%

PROCEDURE

实验过程

The title compound (10.5 g, 93%) was prepared from ethyl(2R)-4-(4-bromophenyl)-2-methyl-2-(methylsulfonyl)butanoate, (10.0 g, 27.5 mmol) and bis(pinacolato)diborane (7.69 g, 30.3 mmol) by a procedure analogous to that described for (+/−)-ethyl 2-methyl-2-(methylsulfonyl)-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]butanoate as described in Preparation 3 step A.

WORKUP

后处理

  1. customas described in Preparation 3 step A