HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic acid dihydrate → HCID 86731815, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic acid dihydrate | HCID 61373 | — |
| Reactant | Lurasidone | HCID 213046 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 86731815 | HCID 86731815 | — |
Reaction Steps
A mixture consisting of acetone (4750 mL) and lurasidone base (431 g) is refluxed until dissolved. Oxalic acid dihydrate (110 g) is added, and the mixture is cooled to ambient temperature, and then cooled for two hours at 10° C. The solid is filtered, and 435 g of substantially pure lurasidone oxalate is obtained after drying.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853395B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-71523231d30a41849b6f74a7502f2d28 |
| Source note | uspto-grants-2014_10 |