Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 533902Generated: October 29, 2026

(3S)-3-hydroxypyrrolidin-2-one → (R)-3-[6-(2-Cyclopropoxy)-pyridin-3-yloxy]-pyrrolidin-2-one

https://huagongshe.com/reaction/533902

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3S)-3-hydroxypyrrolidin-2-oneHCID 11029774—
Reactant6-(Cyclopropyloxy)-3-pyridinolHCID 86715094—
Product(R)-3-[6-(2-Cyclopropoxy)-pyridin-3-yloxy]-pyrrolidin-2-oneHCID 86715093—

Reaction Steps

Typical Procedure 3 was followed. Reaction of 6-cyclopropoxy-pyridin-3-ol and (S)-3-hydroxy-pyrrolidin-2-one provided the title compound. MS ESI+: m/z=235 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08853412B2
Source datasetuspto-grants-2014_10
ORD IDord-90b87bbab8b24b28975ce8bc264f24dd
Source noteuspto-grants-2014_10