HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86715113, compound → HCID 136377299, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86715113 | HCID 86715113 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 136377299 | HCID 136377299 | — |
Reaction Steps
A solution of 2-(5-(4-methoxybenzyloxy)pyridin-2-yl)-5-methylthiazole (2.0 g) in TFA (10 mL) was stirred at 80° C. for 2 hours. After the reaction was complete, the mixture was evaporated. The residue was purified by chromatography (silica gel, EA/PE 1:2 to EA) to provide the title compound. MS ESI+: m/z=193 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853412B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-0d75dd5b0da3498a8d242f72c3dc43ca |
| Source note | uspto-grants-2014_10 |