HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-(7-Fluoro-3-oxo-indan-5-yl)-3-hydroxy-pyrrolidin-2-one → (R)-3-(2-Bromo-pyridin-4-yloxy)-1-(7-fluoro-3-oxo-indan-5-yl)-pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-(7-Fluoro-3-oxo-indan-5-yl)-3-hydroxy-pyrrolidin-2-one | HCID 86715111 | — |
| Reactant | HCID 178516474 | HCID 178516474 | — |
| Product | (R)-3-(2-Bromo-pyridin-4-yloxy)-1-(7-fluoro-3-oxo-indan-5-yl)-pyrrolidin-2-one | HCID 86715123 | — |
Reaction Steps
Typical Procedure 3 was followed. Reaction of (S)-1-(7-fluoro-3-oxo-indan-5-yl)-3-hydroxy-pyrrolidin-2-one with 2-bromo-pyridin-4-ol provided the title compound. MS ESI+: m/z=405 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853412B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-c9b1c9058cf94cfc914f9f01440f0da6 |
| Source note | uspto-grants-2014_10 |