HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 54349141, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 17beta-Benzoyl-estra-1,3,5(10)-triene-3-carboxylic Acid | HCID 9886601 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 54349141 | HCID 54349141 | — |
Reaction Steps
Into a 250 ml 3-neck round bottom flask is placed 17β-Benzoyl-estra-1,3,5(10)-triene-3-carboxylic acid and an excess of sodium hydroxide. To the flask is added dimethyl sulfoxide as a solvent. The mixture is heated to reflux for 3 hours. Standard workup followed by isolation by preparative HPLC yields title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05618806 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-83c636ab3bb549998c6a6c73a0e2a87c |
| Source note | uspto-grants-1997_04 |