HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Chloro-5-(trifluoromethyl)phenyl)methanol → [3-Bromo-5-(trifluoromethyl)phenyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Chloro-5-(trifluoromethyl)phenyl)methanol | HCID 3857254 | — |
| Reactant | Methyl 3-bromo-5-(trifluoromethyl)benzoate | HCID 18942156 | — |
| Product | [3-Bromo-5-(trifluoromethyl)phenyl]methanol | HCID 29919767 | 35% |
Reaction Steps
The title compound was prepared from methyl 3-bromo-5-(trifluoromethyl)benzoate (Reference Example 37) by a procedure similar to the one described for (3-chloro-5-(trifluoromethyl)phenyl)methanol (Reference Example 30) to provide (3-bromo-5-(trifluoromethyl)phenyl)methanol (7.42 g, 35% (2 steps)) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853215B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-e6c46743bfe84d0ca0ba5b422a1fe056 |
| Source note | uspto-grants-2014_10 |