huagongshe.com
HRID534860

反应详情

EQUATION

反应方程式

HRID 534860 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)CCc1nc(-c2cc(Br)cc(C(F)(F)F)c2)co1
HCID66750877

未命名化合物

结构：O=C(O)CCc1nc(-c2cc(Cl)cc(C(F)(F)F)c2)co1
HCID66751118

未命名化合物

PRODUCTS

生成物

1
结构：O=C(O)CCc1nc(-c2cc(Br)cc(C(F)(F)F)c2)co1
HCID66750893

未命名化合物

收率 85%

PROCEDURE

实验过程

The title compound was prepared from methyl 3-(4-(3-bromo-5-(trifluoromethyl)phenyl)oxazol-2-yl)propanoate (Reference Example 44) by a procedure similar to the one described for 3-(4-(3-chloro-5-(trifluoromethyl)phenyl)oxazol-2-yl)propanoic acid (Reference Example 52) to provide 3-(4-(3-bromo-5-(trifluoromethyl)phenyl)oxazol-2-yl)propanoic acid (0.316 g, 85%) as an off-white powder.