Trifluoroacetic acid → HCID 66792777, compound

Participants

Reaction Steps

A mixture of tert-butyl [3-(4-{[4-(2-tert-butylphenyl)piperazin-1-yl]carbonyl}phenyl)-2-oxoimidazolidin-1-yl]acetate obtained in Example 211 (1.28 g, 2.46 mmol) and trifluoroacetic acid (5 mL) was stirred at room temperature for 4 h. Trifluoroacetic acid was removed in vacuo and water was added to the mixture. The resulting solid was collected, washed with water, diisopropyl ether and dried under reduced pressure to give a solid (1.1 g, 96%).

Provenance & Evidence