1-{[5-(Benzyloxy)-1-methyl-1H-pyrazol-3-yl]carbonyl}-4-(2-tert-butylphenyl)piperazine → HCID 178481911, compound

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A mixture of 1-{[5-(benzyloxy)-1-methyl-1H-pyrazol-3-yl]carbonyl}-4-(2-tert-butylphenyl)piperazine (1.75 g), and palladium-carbon (500 mg) in methanol (150 mL) was stirred under hydrogen atmosphere (5 atm). The mixture was filtered and concentrated under reduced pressure to purify the residue by silica gel column chromatography (ethyl acetate/methanol 100:0 to 90:10). Solvent was removed to obtain a solid (650 mg, 56%). LC/MS; ESI(+) m/z: 343 (M+H)+.

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