反应详情

Compound 1 (0.2 mol) is dissolved in n-pentane (300 mL) and diisopropylamine (0.4 mol) is added dropwise. The reaction mixture is stirred at room temperature for 30 minutes, after which dhisopropylamine hydrochloride is filtered off, solvent is evaporated under reduced pressure and crude product is purified by vacuum distillation. Product 2 is obtained as the fraction boiling at 70° C./0.1 mm Hg and is characterized by 31P NMR arid mass spectroscopy.

1. filtrationafter which dhisopropylamine hydrochloride is filtered off
2. customsolvent is evaporated under reduced pressure and crude product
3. distillationis purified by vacuum distillation