Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 53516생성일: 2026년 10월 25일
Ethylamine → N-(2-chloro-6-methyl-4-trifluoromethyl-3-pyridinyl)-2-ethylamino-3pyridinecarboxamide
https://huagongshe.com/reaction/53516
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethylamine | HCID 6341 | — |
| 반응물 | 2-Chloro-N-(2-chloro-6-methyl-4-trifluoromethyl-3-pyridinyl)-3-pyridinecarboxamide | HCID 19960072 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | N-(2-chloro-6-methyl-4-trifluoromethyl-3-pyridinyl)-2-ethylamino-3pyridinecarboxamide | HCID 19960041 | 37.5% |
반응 단계
Ethylamine (0.4 g) was added to a suspension of 1.3 g of 2-chloro-N-(2-chloro-6-methyl-4-trifluoromethyl-3-pyridinyl)-3-pyridinecarboxamide in 5 ml of xylene, and the resulting mixture heated in a pressure tube for 30 min. at 160° C. The cooled mixture was diluted with ethyl acetate, washed, dried, and concentrated. Column chromatography over silica gel (ethyl acetate/hexane, 1:1) gave 0.5 g of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US05620974 |
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| 출처 데이터셋 | uspto-grants-1997_04 |
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| ORD ID | ord-042ba2b826f648deb0037f7772e8b415 |
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| 출처 메모 | uspto-grants-1997_04 |
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