Benzoyl chloride → HCID 178522337, compound

Participants

Reaction Steps

Benzoyl chloride (2.3 mL, 20 mmol) was added dropwise over 30 min to a stirred suspension of cytosine (1.1 g, 10 mmol) in dry pyridine, and stirring was continued at room temperature for a further 4 h at room temperature. The reaction was quenched by adding a small amount of methanol. The solid was filtered, washed with EtOH and dried in vacuo to give 1.92 g of the desired product 6 (90%).

Provenance & Evidence