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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 535267Generated: October 25, 2026

Phenol, 3-(1,1-dimethylethyl)- → 3-{4-[1-(3-Tert-butylphenoxymethyl)cyclobutylmethoxy]phenyl}hex-4-ynoic acid

https://huagongshe.com/reaction/535267

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenol, 3-(1,1-dimethylethyl)-HCID 11450—
ReactantCyclobutane-1,1-diyldimethanolHCID 4498243—
ReactantMethyl 3-(4-hydroxyphenyl)hex-4-ynoateHCID 57835749—
Product3-{4-[1-(3-Tert-butylphenoxymethyl)cyclobutylmethoxy]phenyl}hex-4-ynoic acidHCID 56592285—

Reaction Steps

Analogously to example 1, cyclobutane-1,1-diyldimethanol, 3-tert-butylphenol and methyl 3-(4-hydroxyphenyl)hex-4-ynoate were used to obtain 3-{4-[1-(3-tert-butylphenoxymethyl)cyclobutylmethoxy]phenyl}hex-4-ynoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859494B2
Source datasetuspto-grants-2014_10
ORD IDord-c178362e27ae4ea39de9bce9de75b92c
Source noteuspto-grants-2014_10