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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 535269Generated: October 30, 2026

M-Cresol → 3-[4-(1-m-Tolyloxymethylcyclobutylmethoxy)phenyl]hex-4-ynoic acid

https://huagongshe.com/reaction/535269

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
ReactantCyclobutane-1,1-diyldimethanolHCID 4498243—
ReactantMethyl 3-(4-hydroxyphenyl)hex-4-ynoateHCID 57835749—
Product3-[4-(1-m-Tolyloxymethylcyclobutylmethoxy)phenyl]hex-4-ynoic acidHCID 56592287—

Reaction Steps

Analogously to example 1, cyclobutane-1,1-diyldimethanol, 3-methylphenol and methyl 3-(4-hydroxyphenyl)hex-4-ynoate were used to obtain 3-[4-(1-m-tolyloxymethylcyclobutylmethoxy)phenyl]hex-4-ynoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859494B2
Source datasetuspto-grants-2014_10
ORD IDord-2b834d2433634f9a818af978ea34e587
Source noteuspto-grants-2014_10