2-(2,5-Dioxopyrrolidin-1-yl)-1,1,3,3-tetramethylisouronium tetrafluoroborate → HCID 59476966, compound

Participants

Reaction Steps

7-[3-(2-{2-[3-(3-Carboxypropionylamino)-propoxy]-ethoxy}-ethoxy)-propylcarbamoyl]-heptanoic acid tert-butyl ester (0.78 g, 1.46 mmol) was activated by means of TSTU as described in example 8 step 4. Crude yield 360 mg, LCMS Method 6: Rt 4.40 min; m/z (M+1) 630; Calcd.: 630. The compound was used without further purification.

Provenance & Evidence