HuagongsheHuagongshe Chemistry Print Report · For research reference only
Succinic anhydride → N-{2-[2-(2-tert-butoxycarbonylamino-ethoxy)-ethoxy]-ethyl}-succinamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Succinic anhydride | HCID 7922 | — |
| Reactant | tert-butyl N-{2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate | HCID 9881394 | — |
| Product | N-{2-[2-(2-tert-butoxycarbonylamino-ethoxy)-ethoxy]-ethyl}-succinamic acid | HCID 57325707 | 98% |
Reaction Steps
Preparation from 1-(t-butyloxycarbonylamino)-3,6-dioxa-8-octanamine) (5 g, 20.16 mmol) and succinic anhydride (2.218 g, 22.18 mmol) gave a thick yellow oil which crystallised on standing (6.5 g, yield 98%). LCMS (Method 6): Rt 2.99 min; m/z (M+1) 349; Calcd.: 349.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859493B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-837dc7ab42e54916bd5c33b713465775 |
| Source note | uspto-grants-2014_10 |