反应详情

A solution of 1.80 g of 2-chloro-N-(2-ethylamino-3-pyridinyl)-5-nitro-3-pyridinecarboxamide in 25 ml of xylene was refluxed for four hours. After concentrating in vacuo, the residue was purified on a silical gel column eluting with 50% ethyl acetate/hexane to give 0.93 g of the title compound.

1. concentrationAfter concentrating in vacuo
2. customthe residue was purified on a silical gel column
3. washeluting with 50% ethyl acetate/hexane