反应详情

温度

55 °C

A mixture of 1-{6-[6-(3-chloro-pyridin-2-yl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-ylamino]-3,3-dimethyl-2,3-dihydro-indol-1-yl}-ethanone (30 mg), EtOH (5 mL), and 5N aqueous HCl (1 mL) was stirred at 55° C. for 10 h. The mixture was concentrated in vacue to give the HCl salt as a light yellow solid (35 mg).

1. concentrationThe mixture was concentrated in vacue