(alpha,alpha,alpha-Trifluoro-4-tolyl)acetic acid → HCID 70976049, compound

Participants

Reaction Steps

The product of Example 1B and 2-[4-(trifluoromethyl)phenyl]acetic acid were treated using a method similar to that described in Example 111 to give the title compound. 1H NMR (500 MHz, DMSO-d6/Deuterium Oxide) δ ppm 8.31 (d, J=7.3 Hz, 1H), 8.04 (d, J=8.0 Hz, 1H), 7.97-8.01 (m, 1H), 7.89-7.93 (m, 1H), 7.72-7.75 (m, 2H), 7.60-7.62 (m, 2H), 3.80-3.83 (m, 6H), 3.03-3.14 (m, 4H); MS (ESI−) M/Z 431 (M−H)−.

Provenance & Evidence