2,5-Difluorophenylacetic acid → HCID 70975857, compound

Participants

Reaction Steps

The product of Example 1B and 2-(2,5-difluorophenyl)acetic acid were treated using a method similar to that described in Example 111 to give the title compound. 1H NMR (500 MHz, DMSO-d6/Deuterium Oxide) δ ppm 8.32 (dd, J=7.9, 1.3 Hz, 1H), 8.03 (d, J=8.0 Hz, 1H), 7.97-8.01 (m, 1H), 7.90-7.93 (m, 1H), 7.36 (ddd, J=9.0, 5.8, 3.2 Hz, 1H), 7.12-7.29 (m, 2H), 3.82-3.84 (m, 4H), 3.75 (s, 2H), 3.09-3.11 (m, 4H); MS (ESI+) M/Z 401 (M+H)+.

Provenance & Evidence