1-Bromo-5-chloro-2-methyl-3-nitrobenzene → 3-Bromo-5-chloro-2-methylaniline

HRID 535730Notes

Reaction equation

HRID 535730 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([N+:9]([O-])=O)[C:3]=1[CH3:12].ClC1C(B2OC(C)(C)C(C)(C)O2)=CC=CC=1N>>[Br:1][C:2]1[C:3]([CH3:12])=[C:4]([CH:5]=[C:6]([Cl:8])[CH:7]=1)[NH2:9]

Participants

3

Reactant 2

HCID 247280961-Bromo-5-chloro-2-methyl-3-nitrobenzeneHCID 581644322-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine

Product 1

HCID 534295933-Bromo-5-chloro-2-methylaniline

Procedure

This material was prepared from 1-bromo-5-chloro-2-methyl-3-nitrobenzene following the procedure used for SM-9, step 3 (96%): LCMS (m/z): 219.9 (MH+); tR=0.99 minute.

Sources & evidence

ORD record
ord-6ad08fe813334864b4a896634c4f1128
Source dataset
uspto-grants-2014_10
Patent number
US08859548B2

Reaction notes

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