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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 536092Generated: October 25, 2026

Ethyl 3-amino-1H-pyrrole-2-carboxylate → 3-({[3-(2-Ethoxyethoxy)pyridin-2-yl]methyl}amino)-1H-pyrrole-2-carboxylic acid ethyl ester

https://huagongshe.com/reaction/536092

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-amino-1H-pyrrole-2-carboxylateHCID 2773439—
Reactant3-(2-Ethoxyethoxy)pyridine-2-carbaldehydeHCID 86623129—
Product3-({[3-(2-Ethoxyethoxy)pyridin-2-yl]methyl}amino)-1H-pyrrole-2-carboxylic acid ethyl esterHCID 6706848273%

Reaction Steps

The title compound (0.17 g, 73%) was prepared in accordance with general method A using 3-(2-ethoxyethoxy)pyridine-2-carbaldehyde (0.21 g, 1.08 mmol) and 3-amino-1H-pyrrole-2-carboxylic acid ethyl ester (0.11 g, 0.717 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859568B2
Source datasetuspto-grants-2014_10
ORD IDord-702e81d9f4a24c2e837c09da13dd0db1
Source noteuspto-grants-2014_10