HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → 2-{[4-Chloro-3-(trifluoromethyl)phenyl]oxy}-5-{[(1-ethyl-2-oxo-1,2-dihydro-4-pyrimidinyl)oxy]methyl}benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | 2-{[4-Chloro-3-(trifluoromethyl)phenyl]oxy}-5-{[(2-oxo-1,2-dihydro-4-pyrimidinyl)oxy]methyl}benzonitrile | HCID 57383181 | — |
| Product | 2-{[4-Chloro-3-(trifluoromethyl)phenyl]oxy}-5-{[(1-ethyl-2-oxo-1,2-dihydro-4-pyrimidinyl)oxy]methyl}benzonitrile | HCID 57383182 | — |
Reaction Steps
The title compound was prepared by a procedure similar to that described for E1 starting from 2-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}-5-{[(2-oxo-2,3-dihydro-4-pyrimidinyl)oxy]methyl}benzonitrile and bromoethane. LC-MS (ESI): m/z 450 [M+H]+; 4.11 min (ret time).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859573B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-359bd690811b454988680386f21682e2 |
| Source note | uspto-grants-2014_10 |