HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl-1,3-thiazole-5-carboxylic acid → HCID 178487303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl-1,3-thiazole-5-carboxylic acid | HCID 736488 | — |
| Reactant | 8-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine;hydrobromide | HCID 178419595 | — |
| Product | HCID 178487303 | HCID 178487303 | — |
Reaction Steps
The procedure used for the preparation of Example 16, Step 2 was used to prepare the title compound from 8-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine hydrobromide (Intermediate I, Step 3) and 2,4-dimethyl-1,3-thiazole-5-carboxylic acid as white solid (4.26 g, 77%): HPLC MS RT=2.05 min, MH+=356.1;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859572B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-b04f1ac55cff4396b5e801b14b099c4d |
| Source note | uspto-grants-2014_10 |