反应详情

The procedure used for the preparation of Example 24, Step 2 was used to prepare the title compound from 5-amino-2,3-dihydroimidazo[1,2-c]quinazolin-8-ol (Intermediate I) and 4-[(3-chloropropyl)sulfonyl]morpholine (Intermediate E). Yield 190 mg (61%). Rf=0.68 in 10% MeOH/CH2Cl2, HPLC MS RT=1.13 min, MH+=394.4.

1. customThe procedure used for the preparation of Example 24, Step 2