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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 536262Generated: October 29, 2026

4-[(3-Chloropropyl)sulfonyl]morpholine → HCID 178508203, compound

https://huagongshe.com/reaction/536262

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(3-Chloropropyl)sulfonyl]morpholineHCID 284407—
Reactant8-methoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine;hydrobromideHCID 178419595—
ProductHCID 178508203HCID 178508203—

Reaction Steps

The procedure used for the preparation of Example 24, Step 2 was used to prepare the title compound from 5-amino-2,3-dihydroimidazo[1,2-c]quinazolin-8-ol (Intermediate I) and 4-[(3-chloropropyl)sulfonyl]morpholine (Intermediate E). Yield 190 mg (61%). Rf=0.68 in 10% MeOH/CH2Cl2, HPLC MS RT=1.13 min, MH+=394.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859572B2
Source datasetuspto-grants-2014_10
ORD IDord-c3df135775ee41428495ce412037b458
Source noteuspto-grants-2014_10