Acetonitrile → HCID 178507819, compound

Participants

Reaction Steps

To a stirred solution of 8-amino-7-chloro-1,4-benzodioxan-5-carboxylic acid (prepared from the corresponding 7-H acid (prepared as in GB 1571278) by chlorination of the protected form) (1.10 g) in acetonitrile was added bis-carbonyldiimidazole (0.77 g). The reaction mixture was stirred at room temperature for 1.5 hours. The solvent was removed under reduced pressure to afford crude 8- amino-7-chloro-1,4-benzodioxan-5-imidazolide.

Provenance & Evidence