HCID 71285801, compound → HCID 71285885, compound

Participants

Reaction Conditions

Reaction Steps

150 ml of phosphoryl chloride was added to 9.100 g (33.67 mmol) of 8-(2-fluorobenzyl)imidazo[1,5-a]pyrimidine-6-carboxamide and it was stirred for 2 h at 120° C. The reaction mixture was concentrated in the rotary evaporator and the residue was mixed with water. The solid was filtered with suction, washed with a little water and dried under high vacuum. 8.02 g (92% of theor.) of the target compound was obtained.

Provenance & Evidence