反应详情

温度

80 °C

2.180 g (purity 73%, approx. 11.82 mmol) of 6-methyl-1H-pyrazolo[3,4-d]pyrimidine and 3.987 g (17.72 mmol) of N-iodosuccinimide were dissolved in 30 ml DMF and heated for 2 h at 80° C. After cooling, the mixture was concentrated in the rotary evaporator and the residue was mixed with dichloromethane, filtered with suction and dried under high vacuum. 7.950 g (approx. 38% purity) of the target compound was obtained.

1. temperatureAfter cooling
2. concentrationthe mixture was concentrated in the rotary evaporator
3. additionthe residue was mixed with dichloromethane
4. filtrationfiltered with suction
5. customdried under high vacuum
6. custom7.950 g (approx. 38% purity) of the target compound was obtained