HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-3-methoxycarbonylmethyl-indan-1-yl-ammonium chloride → 3-Carboxymethyl-5-methoxy-indan-1-yl-ammonium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-3-methoxycarbonylmethyl-indan-1-yl-ammonium chloride | HCID 86656207 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 3-Carboxymethyl-5-methoxy-indan-1-yl-ammonium chloride | HCID 86656208 | — |
Reaction Steps
5-Methoxy-3-methoxycarbonylmethyl-indan-1-yl-ammonium chloride (12.5 g) dissolved in 2 M hydrochloric acid (120 mL) is stirred at reflux temperature for 3 h. Then, the solvent is removed and the residue is azeotropically dried using toluene and further purified by washing with diisopropylether. The product is dried at 50° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859580B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-ed0e7ba0c73f46d5824860b0d3267361 |
| Source note | uspto-grants-2014_10 |