反应详情

5-Methoxy-3-methoxycarbonylmethyl-indan-1-yl-ammonium chloride (12.5 g) dissolved in 2 M hydrochloric acid (120 mL) is stirred at reflux temperature for 3 h. Then, the solvent is removed and the residue is azeotropically dried using toluene and further purified by washing with diisopropylether. The product is dried at 50° C.

1. temperatureat reflux temperature for 3 h
2. customThen, the solvent is removed
3. customthe residue is azeotropically dried
4. customfurther purified
5. washby washing with diisopropylether
6. customThe product is dried at 50° C.