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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 537220Generated: October 25, 2026

Methyl Acrylate → Methyl 3-[4-(3-Benzyloxyphenyl)-4-fluoro-3-methylpiperidin-1-yl]propionate

https://huagongshe.com/reaction/537220

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl AcrylateHCID 7294—
Reactant4-(3-Benzyloxyphenyl)-4-fluoro-3-methylpiperidine hydrochlorideHCID 67463151—
ProductMethyl 3-[4-(3-Benzyloxyphenyl)-4-fluoro-3-methylpiperidin-1-yl]propionateHCID 6746404281%

Reaction Steps

This compound was prepared from 4-(3-benzyloxyphenyl)-4-fluoro-3-methylpiperidine hydrochloride and methyl acrylate as described in Step 1 of Example 4 in 81% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08859777B2
Source datasetuspto-grants-2014_10
ORD IDord-474fc9bc1f19430799ee98378aeac3f7
Source noteuspto-grants-2014_10