HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-indole-4-sulfonyl chloride → N-{3-(2-cyanophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}-1H-indole-4-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-indole-4-sulfonyl chloride | HCID 55280799 | — |
| Reactant | Tert-butyl{3-(2-cyanophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate | HCID 131731952 | — |
| Product | N-{3-(2-cyanophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}-1H-indole-4-sulfonamide | HCID 58504908 | — |
Reaction Steps
Example 70 is prepared from tert-butyl{3-(2-cyanophenyl)-1-[(4-methylpiperidin-1-yl)carbonyl]propyl}carbamate and indole-4-sulfonyl chloride in the same manner that Example 5 is synthesized. ESI MS Calc. 464.2; Found: 465.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08859814B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-8157a4ac1203406aaaf7a5e4fe2c7762 |
| Source note | uspto-grants-2014_10 |