Cyclopentanecarbaldehyde → HCID 68178587, compound

HRID 537465Notes

Reaction equation

HRID 537465 reaction equation
[CH:1]1([CH:6]=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.I[C:9]1[CH:19]=[CH:18][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:11][CH:10]=1>>[CH:1]1([CH:6]([OH:7])[C:9]2[CH:19]=[CH:18][C:12]([C:13]([O:15][CH2:16][CH3:17])=[O:14])=[CH:11][CH:10]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 70106CyclopentanecarbaldehydeHCID 142891Ethyl 4-iodobenzoate

Product 1

HCID 68178587HCID 68178587, compound

Procedure

The title compound was prepared by a method analogous to that described for Intermediate (16) using cyclopentanecarbaldehyde and ethyl 4-iodobenzoate. 1H NMR (400 MHz, CDCl3, δ): 8.01 (d, J=8.4 Hz, 2H), 7.40-7.44 (m, 2H), 4.49 (d, J=8.0 Hz, 1H), 4.39 (q, J=7.2 Hz, 2H), 2.19-2.21 (m, 1H), 1.82-1.87 (m, 2H), 1.41-1.67 (m, 6H), 1.39 (t, J=7.2 Hz, 3H).

Sources & evidence

ORD record
ord-844cc341849841dab0caf4c69b88e93d
Source dataset
uspto-grants-2014_10
Patent number
US08859591B2

Reaction notes

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