HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → 6-Benzyl-2-chloromethyl-6H-imidazo[1,2-c]pyrimidin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 4-Amino-1-benzylpyrimidin-2(1H)-one | HCID 308581 | — |
| Reactant | 2-chloromethyl-6-(4-fluoro-phenyl)-6H-imidazo[1,2-c]pyrimidin-5-one | HCID 68290844 | — |
| Product | 6-Benzyl-2-chloromethyl-6H-imidazo[1,2-c]pyrimidin-5-one | HCID 68291075 | — |
Reaction Steps
6-Benzyl-2-chloromethyl-6H-imidazo[1,2-c]pyrimidin-5-one was prepared from 4-amino-1-benzyl-1H-pyrimidin-2-one and 1,3-dichloroacetone using the methods described above for the preparation of 2-chloromethyl-6-(4-fluoro-phenyl)-6H-imidazo[1,2-c]pyrimidin-5-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08865725B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-c438366e3dfc42969c3ac1032afeb7ab |
| Source note | uspto-grants-2014_10 |