HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Dichloroacetone → 2-Chloromethyl-6-(4-fluoro-phenyl)-8-iodo-6H-imidazo[1,2-c]pyrimidin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Dichloroacetone | HCID 10793 | — |
| Reactant | 2-chloromethyl-6-(4-fluoro-phenyl)-6H-imidazo[1,2-c]pyrimidin-5-one | HCID 68290844 | — |
| Reactant | 4-amino-1-(4-fluoro-phenyl)-5-iodo-1H-pyrimidin-2-one | HCID 68290940 | — |
| Product | 2-Chloromethyl-6-(4-fluoro-phenyl)-8-iodo-6H-imidazo[1,2-c]pyrimidin-5-one | HCID 68290267 | — |
Reaction Steps
2-Chloromethyl-6-(4-fluoro-phenyl)-8-iodo-6H-imidazo[1,2-c]pyrimidin-5-one was prepared from 4-amino-1-(4-fluoro-phenyl)-5-iodo-1H-pyrimidin-2-one and 1,3-dichloroacetone using the methods as described above for the preparation of 2-chloromethyl-6-(4-fluoro-phenyl)-6H-imidazo[1,2-c]pyrimidin-5-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08865725B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-3c601761d328480f999938dadc7a4e6a |
| Source note | uspto-grants-2014_10 |