Sodium Bicarbonate → HCID 71491828, compound

HRID 538660Notes

Reaction equation

HRID 538660 reaction equation
C([O-])(O)=O.[Na+:5].[F:6][C:7]1[CH:8]=[C:9]([C:13]2[CH:14]=[C:15]([OH:26])[C:16]([C:19]([NH:21][CH2:22][C:23]([OH:25])=[O:24])=[O:20])=[N:17][CH:18]=2)[CH:10]=[CH:11][CH:12]=1>CC(C)=O>[F:6][C:7]1[CH:8]=[C:9]([C:13]2[CH:14]=[C:15]([OH:26])[C:16]([C:19]([NH:21][CH2:22][C:23]([O-:25])=[O:24])=[O:20])=[N:17][CH:18]=2)[CH:10]=[CH:11][CH:12]=1.[Na+:5]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 498484851007377-55-0

Product 1

HCID 71491828HCID 71491828, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a vial containing NaHCO3 (41.09 mg) is added a solution of {[5-(3-fluoro-phenyl)-3-hydroxypyridine-2-carbonyl]-amino}acetic acid (6) in acetone (0.64 mL of a 400 mg sample in 5.12 mL). The solution is stirred and the desired product isolated by concentration in vacuo.

Sources & evidence

ORD record
ord-4b4e62fa551445bfbd2687d6f7712205
Source dataset
uspto-grants-2014_10
Patent number
US08865748B2

Reaction notes

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