Succinimide → 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4-methyl-5-oxo-4-propyl-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione

Participants

Role	Name	HCID	Charge
Reactant	Succinimide	HCID 11439	—
Reactant	2-[1-(chloroacetyl)piperidin-4-yl]-5-(3,4-dimethoxyphenyl)-4-methyl-4-propyl-2,4-dihydro-3H-pyrazol-3-one	HCID 66616736	—
Product	1-(2-{4-[3-(3,4-dimethoxyphenyl)-4-methyl-5-oxo-4-propyl-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione	HCID 25116542	—

Reaction Steps

Prepared analogously as described for example 1 using 2-[1-(chloroacetyl)piperidin-4-yl]-5-(3,4-dimethoxyphenyl)-4-methyl-4-propyl-2,4-dihydro-3H-pyrazol-3-one (compound A8) and succinimide as starting compounds.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08865745B2
Source dataset	uspto-grants-2014_10
ORD ID	ord-9cec7d032a78485c82cbe3bb62440217
Source note	uspto-grants-2014_10