HRID538706

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6809

Phthalimide

C8H5NO2

结构：COc1ccc(C2=NN(C3CCN(C(=O)CCl)CC3)C(=O)C2(C)C)cc1OC

HCID66616609

未命名化合物

2 次

PRODUCTS

生成物

结构：COc1ccc(C2=NN(C3CCN(C(=O)CN4C(=O)c5ccccc5C4=O)CC3)C(=O)C2(C)C)cc1OC

HCID25058909

未命名化合物

PROCEDURE

实验过程

Prepared analogously as described for example 1 using 2-[1-(chloroacetyl)piperidin-4-yl]-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one (compound A1) and phthalimide as starting compounds.

WORKUP

后处理

customPrepared analogously

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cb8ca095e6ee4cd4ac3c98cf50de836f
来源数据集: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08865745B2
来源说明: uspto-grants-2014_10

反应 SMILES

Cl[CH2:2][C:3]([N:5]1[CH2:10][CH2:9][CH:8]([N:11]2[C:15](=[O:16])[C:14]([CH3:18])([CH3:17])[C:13]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([O:27][CH3:28])[CH:20]=3)=[N:12]2)[CH2:7][CH2:6]1)=[O:4].[C:29]1(=[O:39])[NH:33][C:32](=[O:34])[C:31]2=[CH:35][CH:36]=[CH:37][CH:38]=[C:30]12>>[CH3:28][O:27][C:21]1[CH:20]=[C:19]([C:13]2[C:14]([CH3:18])([CH3:17])[C:15](=[O:16])[N:11]([CH:8]3[CH2:9][CH2:10][N:5]([C:3](=[O:4])[CH2:2][N:33]4[C:29](=[O:39])[C:30]5[C:31](=[CH:35][CH:36]=[CH:37][CH:38]=5)[C:32]4=[O:34])[CH2:6][CH2:7]3)[N:12]=2)[CH:24]=[CH:23][C:22]=1[O:25][CH3:26]