Butyl iodide → HCID 66851866, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-amino-4,5-dimethylthiazole (2.56 g, 20 mmol) and iodobutane (2.6 mL, 22 mmol) in toluene (20 mL) was refluxed at 80° C. for 48 hours. The mixture was cooled to room temperature and the precipitated solid was filtered, washed with toluene and dried under reduced pressure to provide 2.7 g of crude product as the hydroiodide salt; MS (ESI+) m/z 185 (M+H)+.

Provenance & Evidence