2-Methoxyethylamine → HCID 67034802, compound

HRID 539019Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[N:4][N:5]2[CH:10]=[CH:9][C:8]([NH:11][C@@H:12]([CH:15]([CH3:17])[CH3:16])[CH:13]=O)=[N:7][C:6]=12.[CH3:18][O:19][CH2:20][CH2:21][NH2:22]>>[Br:1][C:2]1[CH:3]=[N:4][N:5]2[CH:10]=[CH:9][C:8]([NH:11][C@@H:12]([CH:15]([CH3:17])[CH3:16])[CH2:13][NH:22][CH2:21][CH2:20][O:19][CH3:18])=[N:7][C:6]=12

Participants

Reactant 2

HCID 80182-Methoxyethylamine

HCID 86667824HCID 86667824, compound

Product 1

HCID 67034802HCID 67034802, compound

Procedure

(S)—N2-(3-bromopyrazolo[1,5-a]pyrimidin-5-yl)-N1-(2-methoxyethyl)-3-methylbutane-1,2-diamine was prepared by the procedure described in Example 15, Step 4, from (S)-2-(3-bromopyrazolo[1,5-a]pyrimidin-5-ylamino)-3-methylbutanal and 2-methoxyethanamine. LCMS (APCI+) m/z 356, 358 [M+H]+.

Sources & evidence

ORD record: ord-b4ed3039ed8c418e81d37889b28406fd
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08865726B2

Reaction notes

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