Aminoacetaldehyde dimethyl acetal → HCID 70654670, compound

HRID 539451Notes

Reaction equation

HRID 539451 reaction equation
[CH:1]([C:4]1[CH:5]=[C:6]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:7]=[C:8]([CH:20]([CH3:22])[CH3:21])[C:9]=1[NH:10][C:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([I:18])[CH:13]=1)([CH3:3])[CH3:2].CO[CH:31](OC)[CH2:32][NH2:33].C(C1C=C(C2C=CC=CC=2)C=C(C(C)C)C=1N1C=CN=C1C1C=CC=C(OC)C=1)(C)C>>[CH:1]([C:4]1[CH:5]=[C:6]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:7]=[C:8]([CH:20]([CH3:22])[CH3:21])[C:9]=1[N:10]1[CH:31]=[CH:32][N:33]=[C:11]1[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([I:18])[CH:13]=1)([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 89728Aminoacetaldehyde dimethyl acetalHCID 70654408HCID 70654408, compoundHCID 70654740HCID 70654740, compound

Product 1

HCID 70654670HCID 70654670, compound

Procedure

The title compound was prepared from N-(3,5-diisopropyl-[1,1′-biphenyl]-4-yl)-3-iodobenzamide and 2,2-dimethoxyethanamine in substantially the same manner, as described in Synthesis of 1-(3,5-diisopropyl-[1,1′-biphenyl]-4-yl)-2-(3-methoxyphenyl)-1H-imidazole.

Sources & evidence

ORD record
ord-cdbcf7cf16674bdf9c301cda823e1790
Source dataset
uspto-grants-2014_10
Patent number
US08871361B2

Reaction notes

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