反应详情

To a solution of 7.74 ml of methanesulfonyl chloride in 100 ml of dichloromethane were added dropwise, at a temperature of 0° C., 23.12 ml of tert-butylamine. On completion of addition, the precipitate was filtered off and the filtrate was washed with 100 ml of 1 N aqueous hydrochloric acid, the organic phase was dried over MgSO4 and the solvent was removed under reduced pressure. The product (14.70 g) was obtained with a molecular weight of 151.2 g/mol (C5H13NO2S).

1. additionOn completion of addition
2. filtrationthe precipitate was filtered off
3. washthe filtrate was washed with 100 ml of 1 N aqueous hydrochloric acid
4. dry with materialthe organic phase was dried over MgSO4
5. customthe solvent was removed under reduced pressure