1-Methylpiperazine → HCID 135566795, compound

HRID 539874Notes

Reaction equation

[Br:1][C:2]1[C:3](=[O:25])[NH:4][C:5]([C:11]2[CH:16]=[C:15]([C:17](=[O:20])[CH2:18]Br)[CH:14]=[CH:13][C:12]=2[O:21][CH2:22][CH2:23][CH3:24])=[N:6][C:7]=1[CH:8]([CH3:10])[CH3:9].[CH3:26][N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>>[Br:1][C:2]1[C:3](=[O:25])[NH:4][C:5]([C:11]2[CH:16]=[C:15]([C:17](=[O:20])[CH2:18][N:30]3[CH2:31][CH2:32][N:27]([CH3:26])[CH2:28][CH2:29]3)[CH:14]=[CH:13][C:12]=2[O:21][CH2:22][CH2:23][CH3:24])=[N:6][C:7]=1[CH:8]([CH3:10])[CH3:9]

Participants

Reactant 2

HCID 531671-Methylpiperazine

HCID 136197298HCID 136197298, compound

Product 1

HCID 135566795HCID 135566795, compound

Procedure

The title compound was prepared by reacting the compound of example 71 with N-methyl piperazine, in the same manner as that of example 72. 1H NMR (CDCl3) δ: 9.23 (1H, d), 8.19 (1H, dd), 7.10 (1H, d), 4.28 (2H, t), 3.77 (2H, s), 3.53 (1H, m), 2.66 (4H, t), 2.52 (4H, t), 2.31 (3H, s), 2.02 (2H, m), 1.29 (6H, d), 1.15 (3H, t).

Sources & evidence

ORD record: ord-a73dd18e5e7d4851933e78197f115ec1
Source dataset: uspto-grants-2014_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08871777B2

Reaction notes

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