HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 20320505, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2,4-Dichloro-6-methylquinazoline | HCID 14256483 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20320505 | HCID 20320505 | — |
Reaction Steps
A mixture of 2,4-dichloro-6-methylquinazoline (500 mg, 2.348 mmol) and a solution of ammonia in tetrahydrofuran (20 mL, 3.0 M) was stirred in an ice-bath for 2 hours. The resulting mixture was concentrated in vauco to afford 454 mg of the crude product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871756B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-31236d62cca54d449e2510febd29d9cc |
| Source note | uspto-grants-2014_10 |