HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → HCID 54596826, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 6-((2S,3'S)-2-Methyl-[1,3']bipyrrolidinyl-1'-yl)-1,2,3,4-tetrahydro-isoquinoline | HCID 67469331 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 54596826 | HCID 54596826 | — |
Reaction Steps
To a solution of 6-((2S,3′S)-2-Methyl-[1,3′]bipyrrolidinyl-1′-yl)-1,2,3,4-tetrahydro-isoquinoline in DCM (7 mL) was added 4-Methoxy-benzoyl chloride in DCM, followed by triethylamine. The reaction was quenched with aq. NaHCO3 and DCM work up. The crude product was purified on a silica gel column to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08871788B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-532e97e25dc94c44890c5248a02e48a2 |
| Source note | uspto-grants-2014_10 |