Trifluoroacetic acid → HCID 71254375, compound

Participants

Reaction Steps

100 mg of tert-butyl (8-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]vinyl}-2-methyl-1,3-dioxodecahydro-2,5,7a-triazacyclopenta[a]indene-5-carboxylate (from Example 10) are dissolved in 9 ml of dichloromethane, and 3 ml of trifluoroacetic acid are added. The mixture is stirred at RT for 2 h, the solvent is then removed under reduced pressure and the crude product is purified by column chromatography (silica gel, MeOH:DCM).

Provenance & Evidence