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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 5410Generated: October 29, 2026

Dichloromethane → Diethyl 2-amino-13-carboxy-1,14-tetradecanedicarboxylate hydrochloride

https://huagongshe.com/reaction/5410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiethyl 2-t-butoxycarbonylamino-13-carboxy-1,14-tetradecanedicarboxylateHCID 19930832—
ProductDiethyl 2-amino-13-carboxy-1,14-tetradecanedicarboxylate hydrochlorideHCID 19930814—

Reaction Steps

Diethyl 2-t-butoxycarbonylamino-13-carboxy-1,14-tetradecanedicarboxylate (3.98 g, 8.40 mmol) is dissolved in methylene chloride (150.0 mL), and hydrogen chloride gas is bubbled through the solution for 15 minutes. The sealed reaction is stirred for 2.5 hours, and then the solvent is evaporated to give diethyl 2-amino-13-carboxy-1,14-tetradecanedicarboxylate hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05244889
Source datasetuspto-grants-1993_09
ORD IDord-856e1c74c5fa4bfaa718c434d3d2dcd8
Source noteuspto-grants-1993_09