Ethyl pyruvate → Propanoic acid, 2-[(4-nitrophenyl)hydrazono]-

HRID 541080Notes

Reaction equation

HRID 541080 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][NH2:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].C([O:14][C:15](=[O:19])[C:16](=O)[CH3:17])C>O>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([NH:10][N:11]=[C:16]([CH3:17])[C:15]([OH:19])=[O:14])=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 12041Ethyl pyruvateHCID 3310889(4-Nitrophenyl)hydrazine

Product 1

HCID 3756951Propanoic acid, 2-[(4-nitrophenyl)hydrazono]-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A suspension in water (150 ml) of 4-nitrophenylhydrazine (15 g, 23 mmol) and 2-oxo-propionic acid ethyl ester (12 g, 100 mmol) was left under stirring at room temperature for 6 hours. The obtained precipitate was filtered and washed to give the ethyl ester of the 2-[(4-nitrophenyl)-hydrazono]-propionic acid.

Workup

  1. filtrationThe obtained precipitate was filtered
  2. washwashed

Sources & evidence

ORD record
ord-3d57aaadebe84df7882db98e4d24f57f
Source dataset
uspto-grants-2014_10
Patent number
US08871948B2

Reaction notes

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